Critical telomerase activity for uncontrolled cell growth
نویسندگان
چکیده
منابع مشابه
Critical telomerase activity for uncontrolled cell growth.
The lengths of the telomere regions of chromosomes in a population of cells are modelled using a chemical master equation formalism, from which the evolution of the average number of cells of each telomere length is extracted. In particular, the role of the telomere-elongating enzyme telomerase on these dynamics is investigated. We show that for biologically relevant rates of cell birth and dea...
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2016
ISSN: 1478-3975
DOI: 10.1088/1478-3975/13/4/046005